deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT03907969

A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.

A Phase I/IIa, Open-Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Ascending Doses of AZD7648 Monotherapy or in Combination With Either Cytotoxic Chemotherapies or Novel Anti-Cancer Agents in Patients With Advanced Malignancies

Sponsor: AstraZeneca

Conditions Advanced Malignancies
Interventions AZD7648 PLD
Updated 27 times since 2019 Last updated: Jan 10, 2024 Started: Oct 9, 2019 Primary completion: Dec 7, 2022 Completion: Dec 7, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Advanced Malignancies, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 27 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~May 2019 – ~Nov 2019 · 6 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

27 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Feb 2023 — Mar 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not Recruiting → Completed

  5. Dec 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

▶ Show 22 earlier versions

  1. Sep 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  2. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Mar 2022 — Jun 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2022 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Nov 2021 — Jan 2022 [monthly]

    Recruiting PHASE1_PHASE2

  7. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1_PHASE2

  9. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

  10. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE1_PHASE2

  11. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  12. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1_PHASE2

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  14. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  15. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Active Not Recruiting → Recruiting

  16. May 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  17. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  18. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

  19. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1_PHASE2

  20. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1_PHASE2

  21. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  22. May 2019 — Nov 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Parexel
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations