Unknown PHASE4 INTERVENTIONAL 2-arm NCT03910998

Impact of Intraoperative Deep Neuromuscular Blockade on NOL-guided Opioid Requirement in LSC Colorectal Surgeries

A Randomized Parallel Design Study to Compare the Impact of Intraoperative Deep Neuromuscular Blockade on Intraoperative NOL-guided Opioid Requirement and Postoperative Early Outcomes in Laparoscopic Colorectal Surgeries

Sponsor: Ciusss de L'Est de l'Île de Montréal

Conditions Laparoscopic Colorectal Surgeries

Interventions Rocuronium IV bolus 0.1 mg/kg guided by TOF 0/4 and PTC≤ 2 Rocuronium IV bolus 0.1 mg/kg guided by TOF that must remain between 1-3 during surgery

Updated 9 times since 2019 Last updated: Apr 4, 2022 Started: May 30, 2019 Primary completion: Jul 1, 2022 Completion: Jul 1, 2022

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Laparoscopic Colorectal Surgeries and is currently ongoing. Ciusss de L'Est de l'Île de Montréal leads this study, which shows 9 recorded versions since 2019 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Unknown PHASE4
Sep 2024 — Sep 2025 [monthly]

Unknown PHASE4
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE4

Status: Unknown Status → Unknown
May 2024 — Jul 2024 [monthly]

Unknown Status PHASE4

Status: Recruiting → Unknown Status
May 2022 — May 2024 [monthly]

Recruiting PHASE4

▶ Show 4 earlier versions

Nov 2021 — May 2022 [monthly]

Recruiting PHASE4

Status: Unknown Status → Recruiting
Oct 2021 — Nov 2021 [monthly]

Unknown Status PHASE4

Status: Not Yet Recruiting → Unknown Status
Jan 2021 — Oct 2021 [monthly]

Not Yet Recruiting PHASE4
May 2019 — Jan 2021 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ciusss de L'Est de l'Île de Montréal
Merck Canada Inc.

Data source: Ciusss de L'Est de l'Île de Montréal

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Montreal East, Canada