deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT03939104

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) (DeTACT-ASIA)

A Multi-centre Randomised Controlled Non-inferiority Trial to Compare the Efficacy, Safety and Tolerability of Triple Artemisinin-based Combination Therapies Versus First-line ACTs + Placebo for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Asia

Sponsor: Mahidol Oxford Tropical Medicine Research Unit

Updated 12 times since 2019 Last updated: Mar 18, 2024 Started: Jun 30, 2021 Primary completion: Jan 6, 2023 Completion: Jan 28, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03939104, this PHASE3 trial focuses on Plasmodium Falciparum Malaria (Uncomplicated) and remains completed. Sponsored by Mahidol Oxford Tropical Medicine Research Unit, it has been updated 12 times since 2021, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jun 2019 – ~Dec 2019 · 6 months · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Oct 2020 · 10 months · monthly snapshotNot Yet Recruiting~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshotRecruiting~Feb 2022 – ~Jun 2023 · 16 months · monthly snapshotRecruiting~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshotRecruiting~Aug 2023 – ~Apr 2024 · 8 months · monthly snapshotRecruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE3

    Status: RecruitingCompleted

  5. Aug 2023 — Apr 2024 [monthly]

    Recruiting PHASE3

Show 7 earlier versions
  1. Jun 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  2. Feb 2022 — Jun 2023 [monthly]

    Recruiting PHASE3

  3. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  4. Jan 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE3

  5. Oct 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE3

  6. Dec 2019 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE3

  7. Jun 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mahidol Oxford Tropical Medicine Research Unit
  • University of Oxford
Data source: University of Oxford

For direct contact, visit the study record on ClinicalTrials.gov .