deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT03948464

Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder (pRESTO)

Repurposing Slow-Release Oral Morphine as a New Oral Alternative for the Treatment of Opioid Use Disorder

Sponsor: Canadian Institutes of Health Research (CIHR)

Updated 7 times since 2019 Last updated: Jan 27, 2022 Started: Dec 6, 2019 Primary completion: Jun 1, 2020 Completion: Jun 1, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study unable to proceed per protocol due to COVID-19 precautions

Listed as NCT03948464, this PHASE3 trial focuses on Fentanyl and Methadone and remains terminated or withdrawn. Sponsored by Canadian Institutes of Health Research (CIHR), it has been updated 7 times since 2019, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jun 2019 – ~Aug 2020 · 14 months · monthly snapshotNot Yet Recruiting~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshotSuspended~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotSuspended~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotSuspended~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  3. Mar 2022 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: SuspendedTerminated

  4. Jan 2021 — Mar 2022 [monthly]

    Suspended PHASE3

  5. Oct 2020 — Jan 2021 [monthly]

    Suspended PHASE3

Show 2 earlier versions
  1. Aug 2020 — Oct 2020 [monthly]

    Suspended PHASE3

    Status: Not Yet RecruitingSuspended

  2. Jun 2019 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Canadian Institutes of Health Research (CIHR)
  • M. Eugenia Socias
  • Mayne Pharma International Pty Ltd
  • Vancouver Foundation
Data source: BC Centre on Substance Use

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations