deltatrials
Recruiting OBSERVATIONAL NCT03958565

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations

Sponsor: Cancer League of Colorado

Conditions Carcinoma, Non-Small-Cell Lung
Interventions Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA] Tyrosine Kinase Inhibitor Zoledronic Acid 4 MG/100 ML Intravenous Solution [ZOMETA]
Updated 15 times since 2019 Last updated: May 15, 2025 Started: Apr 28, 2020 Primary completion: Mar 5, 2028 Completion: Apr 28, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03958565, this observational or N/A phase trial focuses on Carcinoma, Non-Small-Cell Lung and remains actively recruiting participants. Sponsored by Cancer League of Colorado, it has been updated 15 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2019 – ~Jun 2020 · 12 months · monthly snapshot~Jun 2020 – ~Dec 2020 · 6 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Apr 2023 · 10 months · monthly snapshot~Apr 2023 – ~Apr 2024 · 12 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~May 2025 · 4 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – present · 14 months · monthly snapshot

Change History

15 versions recorded

  1. Jun 2025 — Present [monthly]

    Recruiting

  2. May 2025 — Jun 2025 [monthly]

    Recruiting

  3. Jan 2025 — May 2025 [monthly]

    Recruiting

  4. Oct 2024 — Jan 2025 [monthly]

    Recruiting

  5. Sep 2024 — Oct 2024 [monthly]

    Recruiting

▶ Show 10 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  2. Apr 2024 — Jul 2024 [monthly]

    Recruiting

  3. Apr 2023 — Apr 2024 [monthly]

    Recruiting

  4. Jun 2022 — Apr 2023 [monthly]

    Recruiting

  5. Apr 2022 — Jun 2022 [monthly]

    Recruiting

  6. Dec 2021 — Apr 2022 [monthly]

    Recruiting

  7. Jan 2021 — Dec 2021 [monthly]

    Recruiting

  8. Dec 2020 — Jan 2021 [monthly]

    Recruiting

  9. Jun 2020 — Dec 2020 [monthly]

    Recruiting

  10. Jun 2019 — Jun 2020 [monthly]

    Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cancer League of Colorado
  • University of Colorado, Denver
Data source: University of Colorado, Denver

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations