deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT03961672

Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

A Phase II Study of Intermittent Duvelisib Dosing in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Sponsor: City of Hope Medical Center

Conditions Recurrent Chronic Lymphocytic Leukemia Recurrent Small Lymphocytic Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Small Lymphocytic Lymphoma
Interventions Duvelisib
Updated 17 times since 2019 Last updated: Dec 15, 2025 Started: May 13, 2020 Primary completion: Jul 31, 2023 Completion: Oct 26, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Recurrent Chronic Lymphocytic Leukemia and Recurrent Small Lymphocytic Lymphoma, this trial is ongoing. The trial is conducted by City of Hope Medical Center and has accumulated 17 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Jun 2020 · 8 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Oct 2022 · 30 days · monthly snapshot~Oct 2022 – ~Nov 2022 · 31 days · monthly snapshot~Nov 2022 – ~Jun 2023 · 7 months · monthly snapshot~Jun 2023 – ~Mar 2024 · 9 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Aug 2025 · 6 months · monthly snapshot~Aug 2025 – ~Feb 2026 · 6 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

17 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Aug 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Feb 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 12 earlier versions

  1. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Suspended → Active Not Recruiting

  4. Oct 2022 — Nov 2022 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  5. Sep 2022 — Oct 2022 [monthly]

    Recruiting PHASE2

  6. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE2

  7. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  8. Sep 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  9. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

    Status: Active Not Recruiting → Recruiting

  10. Jun 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  11. Oct 2019 — Jun 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  12. Jun 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • City of Hope Medical Center
  • National Cancer Institute (NCI)
Data source: City of Hope Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations