deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT03967197

Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring

Is Lidocaine Useful Before Esophageal Manometry and Ambulatory pH Monitoring? A Randomized Controlled Study

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Conditions Pain, Acute
Updated 11 times since 2019 Last updated: Jan 17, 2023 Started: Aug 6, 2019 Primary completion: Aug 5, 2020 Completion: Aug 5, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Pain, Acute and is currently completed. Centre hospitalier de l'Université de Montréal (CHUM) leads this study, which shows 11 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Study Description(click to expand)

Conventionally, topical nasopharyngeal anesthesia is applied to improve the tolerance of esophageal manometry and ambulatory pH monitoring. However, there is currently no data to support this practice. This randomized controlled trial of lidocaine versus placebo applied before these tests will evaluate the benefit of topical lidocaine anesthesia.

Conventionally, topical nasopharyngeal anesthesia is applied to improve the tolerance of esophageal manometry and ambulatory pH monitoring. However, there is currently no data to support this practice. This randomized controlled trial of lidocaine versus placebo applied before these tests will evaluate the benefit of topical lidocaine anesthesia.

Status Flow

~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshotNot Yet Recruiting~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshotEnrolling By Invitation~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshotEnrolling By Invitation~Oct 2019 – ~Sep 2020 · 11 months · monthly snapshotEnrolling By Invitation~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotCompleted~Jan 2021 – ~Feb 2023 · 25 months · monthly snapshotCompleted~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 7 months · monthly snapshotCompleted~Jan 2026 – present · 3 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Sep 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2/PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  5. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

Show 6 earlier versions
  1. Jan 2021 — Feb 2023 [monthly]

    Completed PHASE2_PHASE3

  2. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE2_PHASE3

    Status: Enrolling By InvitationCompleted

  3. Oct 2019 — Sep 2020 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

  4. Sep 2019 — Oct 2019 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

  5. Aug 2019 — Sep 2019 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

    Status: Not Yet RecruitingEnrolling By Invitation

  6. Jun 2019 — Aug 2019 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Centre hospitalier de l'Université de Montréal (CHUM)
Data source: Centre hospitalier de l'Université de Montréal (CHUM)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations