deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT03997903

Imatinib for Pain in Sickle Cell Anemia (IMPACT)

IMatinib for PAin in Chronic Treatment of Sickle Cell Anemia (IMPACT SCA): A Pilot Study of Imatinib in Patients With Sickle Cell Anemia and Recurrent Vaso-occlusive Pain

Sponsor: Children's Hospital Medical Center, Cincinnati

Conditions Sickle Cell Disease
Interventions Imatinib Mesylate
Updated 11 times since 2019 Last updated: Jan 28, 2026 Started: Feb 26, 2020 Primary completion: Aug 6, 2024 Completion: Aug 6, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

low accrual

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A PHASE1/PHASE2 clinical study on Sickle Cell Disease, this trial is terminated or withdrawn. The trial is conducted by Children's Hospital Medical Center, Cincinnati and has accumulated 11 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jul 2019 – ~Mar 2020 · 8 months · monthly snapshotNot Yet Recruiting~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2021 – ~Nov 2021 · 8 months · monthly snapshotRecruiting~Nov 2021 – ~Sep 2022 · 10 months · monthly snapshotRecruiting~Sep 2022 – ~Jun 2023 · 9 months · monthly snapshotRecruiting~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotRecruiting~Apr 2025 – ~Feb 2026 · 10 months · monthly snapshotTerminated~Feb 2026 – present · 4 months · monthly snapshotTerminated

Change History

11 versions recorded

  1. Feb 2026 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Apr 2025 — Feb 2026 [monthly]

    Terminated PHASE1/PHASE2

    Status: Recruiting → Terminated

  3. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  5. Jun 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

    Phase: EARLY_PHASE1 → PHASE1_PHASE2

▶ Show 6 earlier versions

  1. Sep 2022 — Jun 2023 [monthly]

    Recruiting EARLY_PHASE1

  2. Nov 2021 — Sep 2022 [monthly]

    Recruiting EARLY_PHASE1

  3. Mar 2021 — Nov 2021 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet Recruiting → Recruiting

  4. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  5. Mar 2020 — Jan 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  6. Jul 2019 — Mar 2020 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Hospital Medical Center, Cincinnati
  • Indiana University
  • Purdue University
Data source: Indiana University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations