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Terminated PHASE3 INTERVENTIONAL 2-arm NCT04012073

Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome (IPERPEEP)

Individualized Positive End-expiRatory Pressure Guided by End-Expiratory Lung Volume in Moderate-to-severe Acute resPiratory Distress Syndrome.The IPERPEEP Study

Sponsor: ClinicalTrialCenter

Updated 10 times since 2019 Last updated: Sep 29, 2025 Started: Nov 1, 2022 Primary completion: Jun 30, 2025 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was prematurely terminated following the funder's decision to withdraw financial support.

Listed as NCT04012073, this PHASE3 trial focuses on Respiratory Distress Syndrome, Adult and remains terminated or withdrawn. Sponsored by ClinicalTrialCenter, it has been updated 10 times since 2022, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshotNot Yet Recruiting~Feb 2020 – ~Sep 2020 · 7 months · monthly snapshotNot Yet Recruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotNot Yet Recruiting~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshotNot Yet Recruiting~Jan 2023 – ~Feb 2024 · 13 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotRecruiting~Oct 2025 – present · 9 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE3

    Status: RecruitingTerminated

  2. Sep 2024 — Oct 2025 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  5. Jan 2023 — Feb 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

Show 5 earlier versions
  1. Nov 2022 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE3

  2. Jan 2021 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE3

  3. Sep 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE3

  4. Feb 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE3

  5. Aug 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • ClinicalTrialCenter
  • FerrarioDati
  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS
  • General Electric
Data source: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

For direct contact, visit the study record on ClinicalTrials.gov .