deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT04013555

The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia (TrypNAC-II)

Sponsor: University of Maryland, Baltimore

Updated 17 times since 2019 Last updated: Jan 23, 2026 Started: Jan 20, 2020 Primary completion: Aug 14, 2024 Completion: Aug 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04013555, this PHASE1/PHASE2 trial focuses on Schizoaffective Disorder and Schizophrenia and remains completed. Sponsored by University of Maryland, Baltimore, it has been updated 17 times since 2020, reflecting substantial change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Status Flow

~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Nov 2020 · 8 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Jan 2023 · 12 months · monthly snapshot~Jan 2023 – ~Jan 2024 · 12 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Apr 2025 · 4 months · monthly snapshot~Apr 2025 – ~Feb 2026 · 10 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

17 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Apr 2025 — Feb 2026 [monthly]

    Completed PHASE1/PHASE2

  3. Dec 2024 — Apr 2025 [monthly]

    Completed PHASE1/PHASE2

    Status: RecruitingCompleted

  4. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1/PHASE2

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

Show 12 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  2. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2023 — Jan 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2022 — Jan 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2021 — Jan 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Mar 2020 — Nov 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Jan 2020 — Mar 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  9. Dec 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  10. Nov 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  11. Sep 2019 — Nov 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  12. Aug 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Maryland, Baltimore
Data source: University of Maryland, Baltimore

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations