deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 12-arm NCT04044001

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

A Prospective Phase Ib/IIa, Active-controlled, Randomized, Open-label Study to Evaluate the Safety, Tolerability, Extended Early Bactericidal Activity and Pharmacokinetics of Multiple Oral Doses of BTZ-043 Tablets in Subjects With Newly Diagnosed, Uncomplicated, Smear-positive, Drug-susceptible Pulmonary Tuberculosis

Sponsor: European and Developing Countries Clinical Trials Partnership (EDCTP)

Updated 10 times since 2019 Last updated: Aug 9, 2022 Started: Nov 15, 2019 Primary completion: Mar 3, 2022 Completion: May 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Other Specified Pulmonary Tuberculosis and Pulmonary Tuberculoses, this trial is completed. The trial is conducted by European and Developing Countries Clinical Trials Partnership (EDCTP) and has accumulated 10 data snapshots since 2019. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshotRecruiting~Jan 2020 – ~Dec 2020 · 11 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshotRecruiting~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshotRecruiting~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  4. Mar 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  5. Nov 2021 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

Show 5 earlier versions
  1. Jan 2021 — Nov 2021 [monthly]

    Recruiting PHASE1_PHASE2

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2020 — Dec 2020 [monthly]

    Recruiting PHASE1_PHASE2

  4. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Sep 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • European and Developing Countries Clinical Trials Partnership (EDCTP)
  • German Federal Ministry of Education and Research
  • Michael Hoelscher
  • Radboud University Medical Center
Data source: Ludwig-Maximilians - University of Munich

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations