deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT04078152

Durvalumab Long-Term Safety and Efficacy Study (WAVE)

An Open-Label, Multi-Center, Global Study to Evaluate Long Term Safety and Efficacy in Patients Who Are Receiving or Who Previously Received Durvalumab in Other Protocols (WAVE)

Sponsor: AstraZeneca

Conditions Solid Tumor
Interventions Durvalumab
Updated 28 times since 2019 Last updated: Nov 26, 2024 Started: Sep 5, 2019 Primary completion: Oct 31, 2022 Completion: Oct 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Solid Tumor and is currently completed. AstraZeneca leads this study, which shows 28 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~May 2021 · 3 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~May 2022 · 4 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Oct 2023 · 5 months · monthly snapshot~Oct 2023 – ~Mar 2024 · 5 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 9 months · monthly snapshot

Change History

28 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE4

  3. Jan 2025 — Sep 2025 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  4. Oct 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE4

  5. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE4

▶ Show 23 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE4

  2. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE4

  3. Oct 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE4

  4. May 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE4

  5. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE4

  6. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE4

  7. May 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE4

  8. Jan 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  9. Oct 2021 — Jan 2022 [monthly]

    Recruiting PHASE4

  10. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE4

  11. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

  12. Feb 2021 — May 2021 [monthly]

    Recruiting PHASE4

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE4

  14. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

  15. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE4

  16. Aug 2020 — Oct 2020 [monthly]

    Recruiting PHASE4

  17. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE4

  18. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE4

  19. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE4

  20. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE4

  21. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE4

  22. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE4

  23. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE4

    First recorded

Sep 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • CISCRP
  • Iqvia Pty Ltd
  • Medidata Solutions
  • Parexel
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Amsterdam, Netherlands , Arkhangelsk, Russia , Arnhem, Netherlands , Augusta, United States , Badalona, Spain , Baltimore, United States , Bangkok, Thailand , Barcelona, Spain , Bellinzona, Switzerland and 94 more locations