Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT04079517

Karolinska Interventional Study of Mammograhic Density (Karisma-1) (Karisma-1)

A Randomized, Open Pilot Study to Investigate the Mammographic Density Reduction on Healthy Women, Within the Karma Cohort, for Two Different Doses of Tamoxifen

Sponsor: Karolinska Institutet

Conditions Breast Cancer Mammographic Density

Interventions Tamoxifen

Updated 5 times since 2019 Last updated: Feb 5, 2025 Started: Mar 31, 2015 Primary completion: Feb 29, 2016 Completion: Mar 31, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Breast Cancer and Mammographic Density and is currently completed. Karolinska Institutet leads this study, which shows 5 recorded versions since 2015 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

5 versions recorded

Mar 2025 — Present [monthly]

Completed PHASE1/PHASE2
Sep 2024 — Mar 2025 [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1_PHASE2
Oct 2019 — Jan 2021 [monthly]

Completed PHASE1_PHASE2

First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Karolinska Institutet

Data source: Karolinska Institutet

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.