deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT04089189

Study of IMP4297 in Patients With BRCA1/2 Mutation Ovarian Cancer (SABRINA)

A Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of IMP4297 Capsules in Subjects With Germline and/or Somatic BRCA1/2 Mutation Positive Advanced Ovarian Cancer With at Least 2 Prior Lines of Standard Systemic Therapy

Sponsor: Impact Therapeutics, Inc.

Conditions Ovarian Cancer
Interventions IMP4297
Updated 10 times since 2019 Last updated: Jan 26, 2026 Started: Oct 28, 2019 Primary completion: Jun 30, 2023 Completion: Dec 17, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Ovarian Cancer and is currently completed. Impact Therapeutics, Inc. leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshotRecruiting~Mar 2020 – ~Dec 2020 · 9 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotRecruiting~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotUnknown~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshotCompleted~Feb 2026 – present · 4 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE2

  2. Oct 2025 — Feb 2026 [monthly]

    Completed PHASE2

    Status: UnknownCompleted

  3. Sep 2024 — Oct 2025 [monthly]

    Unknown PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  5. Dec 2022 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

Show 5 earlier versions
  1. Jan 2021 — Dec 2022 [monthly]

    Recruiting PHASE2

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  3. Mar 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  4. Dec 2019 — Mar 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Oct 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Impact Therapeutics, Inc.
Data source: Impact Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations