deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04099836

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

Single Arm Phase 2 Trial of Atezolizumab and Bevacizumab in Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer in Patients With Progressive Disease After Receiving Osimertinib (TOP 1901)

Sponsor: Duke University

Updated 15 times since 2019 Last updated: Dec 12, 2023 Started: Jul 9, 2020 Primary completion: Nov 13, 2022 Completion: Jun 15, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

low accrual

This PHASE2 trial investigates Non Small Cell Lung Cancer and is currently terminated or withdrawn. Duke University leads this study, which shows 15 recorded versions since 2020 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jan 2022 · 10 months · monthly snapshot~Jan 2022 – ~Jun 2022 · 5 months · monthly snapshot~Jun 2022 – ~May 2023 · 11 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Jan 2024 · 6 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jan 2024 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Jul 2023 — Jan 2024 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  5. May 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

Show 10 earlier versions
  1. Jun 2022 — May 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: SuspendedActive Not Recruiting

  2. Jan 2022 — Jun 2022 [monthly]

    Suspended PHASE2

    Status: RecruitingSuspended

  3. Mar 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  4. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  5. Sep 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  6. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Apr 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE2

  8. Feb 2020 — Apr 2020 [monthly]

    Not Yet Recruiting PHASE2

  9. Dec 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE2

  10. Oct 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Duke University
Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations