Completed NA INTERVENTIONAL 2-arm NCT04108130

An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study (PRIME-AIR)

Sponsor: Columbia University

Conditions Postoperative Pulmonary Complications

Interventions Individualization of Neuromuscular Blockade Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization Postoperative Ambulation Postoperative Incentive Spirometry Preoperative Education

Updated 15 times since 2019 Last updated: Sep 16, 2025 Started: Jan 29, 2020 Primary completion: Jul 13, 2023 Completion: Jul 13, 2023

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04108130, this NA trial focuses on Postoperative Pulmonary Complications and remains completed. Sponsored by Columbia University, it has been updated 15 times since 2020, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

15 versions recorded

Nov 2025 — Present [monthly]

Completed NA
Sep 2025 — Nov 2025 [monthly]

Completed NA
Aug 2025 — Sep 2025 [monthly]

Completed NA

Status: Unknown → Completed
Mar 2025 — Aug 2025 [monthly]

Unknown NA

Status: Recruiting → Unknown
Sep 2024 — Mar 2025 [monthly]

Recruiting NA

▶ Show 10 earlier versions

Jul 2024 — Sep 2024 [monthly]

Recruiting NA
Mar 2023 — Jul 2024 [monthly]

Recruiting NA
Sep 2022 — Mar 2023 [monthly]

Recruiting NA
Mar 2021 — Sep 2022 [monthly]

Recruiting NA
Jan 2021 — Mar 2021 [monthly]

Recruiting NA
Oct 2020 — Jan 2021 [monthly]

Recruiting NA

Phase: PHASE4 → NA
Sep 2020 — Oct 2020 [monthly]

Recruiting PHASE4
Mar 2020 — Sep 2020 [monthly]

Recruiting PHASE4

Status: Not Yet Recruiting → Recruiting
Nov 2019 — Mar 2020 [monthly]

Not Yet Recruiting PHASE4
Oct 2019 — Nov 2019 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Data source: Columbia University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aurora, United States , Boston, United States , Durham, United States , Evanston, United States , Miami, United States , New York, United States , Omaha, United States , Rochester, United States , San Francisco, United States , Stanford, United States and 2 more locations