deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT04139057

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Single-Arm Trial of EBV-Specific TCR-T Cells With Anti-PD1 Auto-secreted Element in the Treatment of EBV-Positive Head and Neck Carcinoma

Sponsor: TCRCure Biopharma Ltd.

Updated 12 times since 2019 Last updated: Jan 16, 2026 Started: Mar 1, 2019 Primary completion: Jan 15, 2026 Completion: Jan 15, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04139057, this PHASE1/PHASE2 trial focuses on Head and Neck Squamous Cell Carcinoma and remains completed. Sponsored by TCRCure Biopharma Ltd., it has been updated 12 times since 2019, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Nov 2019 – ~Aug 2020 · 9 months · monthly snapshotRecruiting~Aug 2020 – ~Dec 2020 · 4 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotRecruiting~Jan 2022 – ~Dec 2022 · 11 months · monthly snapshotRecruiting~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshotUnknown Status~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotRecruiting~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshotRecruiting~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE1/PHASE2

    Status: RecruitingCompleted

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting PHASE1/PHASE2

  3. Nov 2024 — Sep 2025 [monthly]

    Recruiting PHASE1/PHASE2

  4. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

Show 7 earlier versions
  1. Mar 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Unknown StatusRecruiting

  2. Dec 2022 — Mar 2023 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: RecruitingUnknown Status

  3. Jan 2022 — Dec 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2021 — Jan 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  6. Aug 2020 — Dec 2020 [monthly]

    Recruiting PHASE1_PHASE2

  7. Nov 2019 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Mar 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • TCRCure Biopharma Ltd.
  • Xinqiao Hospital of Chongqing
Data source: Xinqiao Hospital of Chongqing

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations