deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT04146298

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer

Clinical Trial Evaluating the Safety and Activity of Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer

Sponsor: Changhai Hospital

Updated 14 times since 2019 Last updated: Dec 18, 2025 Started: Oct 21, 2021 Primary completion: Jun 30, 2027 Completion: Dec 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Advanced Cancer and Pancreatic Cancer, this trial is actively recruiting participants. The trial is conducted by Changhai Hospital and has accumulated 14 data snapshots since 2021. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Jun 2020 · 4 months · monthly snapshot~Jun 2020 – ~Oct 2020 · 4 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Mar 2022 · 9 months · monthly snapshot~Mar 2022 – ~Jul 2022 · 4 months · monthly snapshot~Jul 2022 – ~Oct 2023 · 15 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshot~Oct 2025 – ~Jan 2026 · 3 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

14 versions recorded
  1. Jan 2026 — Present [monthly]

    Recruiting PHASE1/PHASE2

    Status: UnknownRecruiting

  2. Oct 2025 — Jan 2026 [monthly]

    Unknown PHASE1/PHASE2

    Status: RecruitingUnknown

  3. Sep 2024 — Oct 2025 [monthly]

    Recruiting PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. Oct 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

Show 9 earlier versions
  1. Jul 2022 — Oct 2023 [monthly]

    Recruiting PHASE1_PHASE2

  2. Mar 2022 — Jul 2022 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jun 2021 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE1_PHASE2

  5. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jun 2020 — Oct 2020 [monthly]

    Recruiting PHASE1_PHASE2

  7. Feb 2020 — Jun 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Dec 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  9. Nov 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Changhai Hospital
Data source: Changhai Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations