deltatrials
Unknown PHASE1 INTERVENTIONAL 1-arm NCT04156347

Topotecan Episcleral Plaque for Treatment of Retinoblastoma

A Phase I Study of Sequestered Transscleral, Controlled-Release Topotecan Delivered From an Episcleral Reservoir in Retinoblastoma Eyes

Sponsor: Targeted Therapy Technologies, LLC

Conditions Retinoblastoma
Updated 12 times since 2019 Last updated: Oct 27, 2023 Started: Jun 16, 2021 Primary completion: Oct 1, 2024 Completion: Oct 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Retinoblastoma and is currently ongoing. Targeted Therapy Technologies, LLC leads this study, which shows 12 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2019 – ~Apr 2020 · 4 months · monthly snapshotNot Yet Recruiting~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotRecruiting~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshotRecruiting~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshotRecruiting~Feb 2023 – ~May 2023 · 3 months · monthly snapshotRecruiting~May 2023 – ~Nov 2023 · 6 months · monthly snapshotRecruiting~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~May 2025 · 8 months · monthly snapshotActive Not Recruiting~May 2025 – present · 15 months · monthly snapshotUnknown

Change History

12 versions recorded
  1. May 2025 — Present [monthly]

    Unknown PHASE1

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Nov 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. May 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

Show 7 earlier versions
  1. Feb 2023 — May 2023 [monthly]

    Recruiting PHASE1

  2. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  3. Oct 2021 — Sep 2022 [monthly]

    Recruiting PHASE1

  4. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  5. Jan 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1

  6. Apr 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

  7. Dec 2019 — Apr 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Targeted Therapy Technologies, LLC
Data source: Targeted Therapy Technologies, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations