deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT04166565

Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease (EMN19)

Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease. The ANTARES Study

Sponsor: Janssen, LP

Updated 10 times since 2019 Last updated: Apr 14, 2025 Started: Oct 31, 2019 Primary completion: Mar 31, 2027 Completion: Mar 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Extramedullary Plasmacytoma and Multiple Myeloma and is currently ongoing. Janssen, LP leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotRecruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotRecruiting~Mar 2021 – ~Dec 2022 · 21 months · monthly snapshotRecruiting~Dec 2022 – ~Mar 2024 · 15 months · monthly snapshotActive Not Recruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotActive Not Recruiting~Nov 2024 – ~May 2025 · 6 months · monthly snapshotActive Not Recruiting~May 2025 – ~Sep 2025 · 4 months · monthly snapshotActive Not Recruiting~Sep 2025 – present · 12 months · monthly snapshotActive Not Recruiting

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. May 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

Show 5 earlier versions
  1. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2022 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Mar 2021 — Dec 2022 [monthly]

    Recruiting PHASE2

  4. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  5. Dec 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

    First recorded

Oct 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen, LP
  • Stichting European Myeloma Network
Data source: European Myeloma Network B.V.

For direct contact, visit the study record on ClinicalTrials.gov .