deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT04167969

The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer

Molecular Phenotyping and Image-Guided Surgical Treatment of Prostate Cancer Using Ultrasmall Silica Nanoparticles

Sponsor: Cornell University/Weill Cornell Medical Center

Conditions Prostate Cancer
Interventions (64Cu)-NOTA-PSMAi-PEG-Cy5.5-C' dot tracer, or (89Zr)-DFO-PSMAi-PEG-Cy5.5-C' dots Blood and urine sampling PET/MRI/fluorescence imaging laparoscopic radical prostatectomy and bilateral pelvic LN dissection or a salvage lymph node dissection
Updated 15 times since 2019 Last updated: Oct 9, 2025 Started: Feb 17, 2021 Primary completion: Nov 30, 2026 Completion: Nov 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Prostate Cancer and is currently actively recruiting participants. Cornell University/Weill Cornell Medical Center leads this study, which shows 15 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Apr 2022 · 6 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Mar 2024 · 11 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Aug 2025 · 5 months · monthly snapshot~Aug 2025 – ~Nov 2025 · 3 months · monthly snapshot~Nov 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded

  1. Nov 2025 — Present [monthly]

    Recruiting PHASE1

  2. Aug 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  3. Mar 2025 — Aug 2025 [monthly]

    Recruiting PHASE1

  4. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

▶ Show 10 earlier versions

  1. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  2. Apr 2023 — Mar 2024 [monthly]

    Recruiting PHASE1

  3. Apr 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

  4. Oct 2021 — Apr 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  6. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  7. Jul 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  8. May 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  9. Feb 2020 — May 2020 [monthly]

    Recruiting PHASE1

  10. Dec 2019 — Feb 2020 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cornell University/Weill Cornell Medical Center
  • Memorial Sloan Kettering Cancer Center
  • National Cancer Institute (NCI)
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations