deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT04177823

A Study of Belantamab Mafodotin to Investigate Safety, Tolerability, Pharmacokinetics, Immunogenicity and Clinical Activity in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Clinical Activity of the Antibody Drug Conjugate GSK2857916 in Chinese Participants With Relapsed/Refractory Multiple Myeloma Who Have Failed At Least Two Lines of Previous Treatment, Containing an Alkylator, a Proteasome Inhibitor and an Immunomodulatory Agent

Sponsor: GlaxoSmithKline

Updated 14 times since 2019 Last updated: Feb 28, 2025 Started: Dec 9, 2019 Primary completion: Dec 30, 2021 Completion: Dec 30, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04177823, this PHASE1 trial focuses on Multiple Myeloma and remains completed. Sponsored by GlaxoSmithKline, it has been updated 14 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2024 · 26 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 17 months · monthly snapshot

Change History

14 versions recorded
  1. Apr 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Apr 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. May 2024 — Jul 2024 [monthly]

    Completed PHASE1

  5. Mar 2022 — May 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 9 earlier versions
  1. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Nov 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Jul 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  6. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  7. Mar 2020 — Jun 2020 [monthly]

    Recruiting PHASE1

  8. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  9. Dec 2019 — Feb 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations