deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT04197479

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients (MAESTRO-NAFLD1)

A 52-Week, Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD) (MAESTRO-NAFLD-1)

Sponsor: Madrigal Pharmaceuticals, Inc.

Updated 11 times since 2020 Last updated: Aug 30, 2023 Started: Dec 16, 2019 Primary completion: Jan 6, 2023 Completion: Jan 6, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04197479, this PHASE3 trial focuses on Non-Alcoholic Fatty Liver Disease and remains completed. Sponsored by Madrigal Pharmaceuticals, Inc., it has been updated 11 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshotRecruiting~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshotRecruiting~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshotRecruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotRecruiting~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotRecruiting~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshotActive Not Recruiting~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshotCompleted~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Oct 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Sep 2023 — Oct 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Sep 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Jan 2021 — Sep 2022 [monthly]

    Recruiting PHASE3

  3. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  4. Jun 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  5. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  6. Jan 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

    First recorded

Dec 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Madrigal Pharmaceuticals, Inc.
Data source: Madrigal Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .