deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04226547

Amplatzer Amulet LAAO vs. NOAC (CATALYST)

Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants

Sponsor: Abbott Medical Devices

Conditions Atrial Fibrillation Bleeding Stroke
Interventions Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder) Non-Vitamin K Oral Antagonists
Updated 32 times since 2020 Last updated: Feb 6, 2026 Started: Jul 7, 2020 Primary completion: Jan 31, 2029 Completion: Apr 30, 2031
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Atrial Fibrillation and Bleeding and is currently ongoing. Abbott Medical Devices leads this study, which shows 32 recorded versions since 2020 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Feb 2020 – ~Aug 2020 · 6 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

32 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting NA

  3. Jun 2025 — Sep 2025 [monthly]

    Recruiting NA

  4. Mar 2025 — Jun 2025 [monthly]

    Recruiting NA

  5. Feb 2025 — Mar 2025 [monthly]

    Recruiting NA

▶ Show 27 earlier versions

  1. Sep 2024 — Feb 2025 [monthly]

    Recruiting NA

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting NA

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting NA

  4. May 2024 — Jul 2024 [monthly]

    Recruiting NA

  5. Feb 2024 — May 2024 [monthly]

    Recruiting NA

  6. Oct 2023 — Feb 2024 [monthly]

    Recruiting NA

  7. Aug 2023 — Oct 2023 [monthly]

    Recruiting NA

  8. Jun 2023 — Aug 2023 [monthly]

    Recruiting NA

  9. Mar 2023 — Jun 2023 [monthly]

    Recruiting NA

  10. Feb 2023 — Mar 2023 [monthly]

    Recruiting NA

  11. Nov 2022 — Feb 2023 [monthly]

    Recruiting NA

  12. Sep 2022 — Nov 2022 [monthly]

    Recruiting NA

  13. Jul 2022 — Sep 2022 [monthly]

    Recruiting NA

  14. May 2022 — Jul 2022 [monthly]

    Recruiting NA

  15. Mar 2022 — May 2022 [monthly]

    Recruiting NA

  16. Dec 2021 — Mar 2022 [monthly]

    Recruiting NA

  17. Nov 2021 — Dec 2021 [monthly]

    Recruiting NA

  18. Oct 2021 — Nov 2021 [monthly]

    Recruiting NA

  19. Sep 2021 — Oct 2021 [monthly]

    Recruiting NA

  20. May 2021 — Sep 2021 [monthly]

    Recruiting NA

  21. Apr 2021 — May 2021 [monthly]

    Recruiting NA

  22. Feb 2021 — Apr 2021 [monthly]

    Recruiting NA

  23. Jan 2021 — Feb 2021 [monthly]

    Recruiting NA

  24. Oct 2020 — Jan 2021 [monthly]

    Recruiting NA

  25. Sep 2020 — Oct 2020 [monthly]

    Recruiting NA

  26. Aug 2020 — Sep 2020 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  27. Feb 2020 — Aug 2020 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Abbott Medical Devices
Data source: Abbott Medical Devices

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aarhus, Denmark , Adelaide, Australia , Albuquerque, United States , Altamonte Springs, United States , Asheville, United States , Atlanta, United States , Austin, United States , Bad Segeberg, Germany , Baltimore, United States , Barcelona, Spain and 101 more locations