deltatrials
Recruiting PHASE1 INTERVENTIONAL 7-arm NCT04227847

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

A Phase 1 Study of SEA-CD70 in Myeloid Malignancies

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Conditions Acute Myeloid Leukemia Myelodysplastic Syndrome
Interventions SEA-CD70 Venetoclax azacitidine
Updated 38 times since 2020 Last updated: Dec 5, 2025 Started: Aug 7, 2020 Primary completion: Jul 4, 2027 Completion: Jul 3, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Acute Myeloid Leukemia and Myelodysplastic Syndrome, this trial is actively recruiting participants. The trial is conducted by Seagen, a wholly owned subsidiary of Pfizer and has accumulated 38 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Mar 2024 · 2 months · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Apr 2025 · 5 months · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Jan 2026 · 2 months · monthly snapshot~Jan 2026 – present · 7 months · monthly snapshot

Change History

38 versions recorded

  1. Jan 2026 — Present [monthly]

    Recruiting PHASE1

  2. Nov 2025 — Jan 2026 [monthly]

    Recruiting PHASE1

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  4. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  5. Jun 2025 — Aug 2025 [monthly]

    Recruiting PHASE1

▶ Show 33 earlier versions

  1. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  2. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE1

  3. Nov 2024 — Apr 2025 [monthly]

    Recruiting PHASE1

  4. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  6. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  7. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  8. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

  9. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE1

  10. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  11. Jan 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  12. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  13. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  14. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  15. Aug 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  16. Jun 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  17. Mar 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  18. Jan 2023 — Mar 2023 [monthly]

    Recruiting PHASE1

  19. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  20. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  21. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  22. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  23. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  24. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE1

  25. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE1

  26. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

  27. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  28. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE1

  29. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  30. Sep 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

  31. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  32. Apr 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE1

    Status: Recruiting → Not Yet Recruiting

  33. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Seagen, a wholly owned subsidiary of Pfizer
Data source: Seagen Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Birmingham, United States , Boston, United States , Bunkyo-ku, Japan , Charleston, United States , Cleveland, United States , Columbus, United States , Dallas, United States , Denver, United States , Detroit, United States , Duarte, United States and 14 more locations