deltatrials
Unknown OBSERVATIONAL NCT04259255

Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)

Sponsor: Massachusetts General Hospital

Updated 16 times since 2020 Last updated: Aug 23, 2023 Started: Oct 21, 2019 Primary completion: Mar 31, 2024 Completion: Mar 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04259255, this observational or N/A phase trial focuses on ALS and Amyotrophic Lateral Sclerosis and remains ongoing. Sponsored by Massachusetts General Hospital, it has been updated 16 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Jan 2022 · 7 months · monthly snapshot~Jan 2022 – ~Sep 2022 · 8 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Jan 2026 · 3 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

16 versions recorded
  1. Jan 2026 — Present [monthly]

    Unknown

  2. Oct 2025 — Jan 2026 [monthly]

    Unknown

    Status: Active Not RecruitingUnknown

  3. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting

  4. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

Show 11 earlier versions
  1. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting

    Status: RecruitingActive Not Recruiting

  2. Feb 2023 — Sep 2023 [monthly]

    Recruiting

  3. Sep 2022 — Feb 2023 [monthly]

    Recruiting

  4. Jan 2022 — Sep 2022 [monthly]

    Recruiting

  5. Jun 2021 — Jan 2022 [monthly]

    Recruiting

  6. Apr 2021 — Jun 2021 [monthly]

    Recruiting

  7. Jan 2021 — Apr 2021 [monthly]

    Recruiting

  8. Sep 2020 — Jan 2021 [monthly]

    Recruiting

  9. Aug 2020 — Sep 2020 [monthly]

    Recruiting

  10. Apr 2020 — Aug 2020 [monthly]

    Recruiting

  11. Mar 2020 — Apr 2020 [monthly]

    Recruiting

    First recorded

Oct 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Massachusetts General Hospital
  • Tanabe Pharma America, Inc.
Data source: Tanabe Pharma America, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .