Recruiting PHASE4 INTERVENTIONAL 2-arm NCT04262206

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults (PREVENTABLE)

PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE)

Sponsor: Duke University

Conditions Cardiovascular Diseases Cognitive Impairment, Mild Dementia

Interventions Atorvastatin 40 Mg Oral Tablet Placebo oral tablet

Updated 18 times since 2020 Last updated: Nov 4, 2025 Started: Sep 1, 2020 Primary completion: Dec 31, 2026 Completion: Dec 31, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Cardiovascular Diseases and Cognitive Impairment, Mild, this trial is actively recruiting participants. The trial is conducted by Duke University and has accumulated 18 data snapshots since 2020. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

18 versions recorded

Dec 2025 — Present [monthly]

Recruiting PHASE4
Sep 2025 — Dec 2025 [monthly]

Recruiting PHASE4
Jul 2025 — Sep 2025 [monthly]

Recruiting PHASE4
Sep 2024 — Jul 2025 [monthly]

Recruiting PHASE4
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE4

▶ Show 13 earlier versions

Feb 2024 — Jul 2024 [monthly]

Recruiting PHASE4
May 2023 — Feb 2024 [monthly]

Recruiting PHASE4
Sep 2022 — May 2023 [monthly]

Recruiting PHASE4
Apr 2022 — Sep 2022 [monthly]

Recruiting PHASE4
Sep 2021 — Apr 2022 [monthly]

Recruiting PHASE4
Apr 2021 — Sep 2021 [monthly]

Recruiting PHASE4
Jan 2021 — Apr 2021 [monthly]

Recruiting PHASE4
Dec 2020 — Jan 2021 [monthly]

Recruiting PHASE4
Nov 2020 — Dec 2020 [monthly]

Recruiting PHASE4
Oct 2020 — Nov 2020 [monthly]

Recruiting PHASE4

Status: Not Yet Recruiting → Recruiting
Aug 2020 — Oct 2020 [monthly]

Not Yet Recruiting PHASE4
May 2020 — Aug 2020 [monthly]

Not Yet Recruiting PHASE4
Mar 2020 — May 2020 [monthly]

Not Yet Recruiting PHASE4

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
Wake Forest University Health Sciences

Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Asheville, United States , Atlanta, United States , Baltimore, United States , Bay Pines, United States , Birmingham, United States , Boston, United States , Chapel Hill, United States , Charleston, United States , Charlotte, United States and 61 more locations