deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT04272801

Pre-Operative Window of Adjuvant Endocrine Therapy to Inform RT Decisions in Older Women With Early-Stage Breast Cancer (POWER)

Pre-Operative Window of Adjuvant Endocrine Therapy to Inform Radiation Therapy Decisions In Older Women With Early-Stage Breast Cancer

Sponsor: National Cancer Institute (NCI)

Conditions Breast Cancer Female
Interventions Patient reported outcomes tamoxifen, letrozole, anastrozole, or exemestane
Updated 13 times since 2020 Last updated: Sep 25, 2025 Started: Apr 7, 2020 Primary completion: Jun 5, 2024 Completion: Jun 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Breast Cancer Female and is currently ongoing. National Cancer Institute (NCI) leads this study, which shows 13 recorded versions since 2020 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshotRecruiting~Apr 2022 – ~Feb 2023 · 10 months · monthly snapshotRecruiting~Feb 2023 – ~Nov 2023 · 9 months · monthly snapshotRecruiting~Nov 2023 – ~Feb 2024 · 3 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotActive Not Recruiting~Aug 2025 – ~Nov 2025 · 3 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshotActive Not Recruiting

Change History

13 versions recorded

  1. Nov 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Aug 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Aug 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

▶ Show 8 earlier versions

  1. Nov 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

  2. Feb 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

    Phase: PHASE1 → PHASE2

  3. Apr 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  4. Sep 2021 — Apr 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  6. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  7. May 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  8. Mar 2020 — May 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Shayna Showalter, MD
Data source: University of Virginia

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations