Unknown PHASE3 INTERVENTIONAL 1-arm NCT04287660

Study of BiRd Regimen Combined With BCMA CAR T-cell Therapy in Newly Diagnosed Multiple Myeloma (MM) Patients

A Phase 3, Single Arm, Multi-Center Study to Assess the Efficacy and Safety of Clarithromycin(Biaxin)-Lenalidomide-Low-Dose-Dexamethasone (BiRd) Combined With B-cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor (CAR) T-cell Therapy in Patients With Newly Diagnosed Multiple Myeloma

Sponsor: Affiliated Hospital of Jiangnan University

Conditions Multiple Myeloma

Interventions clarithromycin, lenalidomide, dexamethasone and autologous BCMA-directed CAR T-cells

Updated 9 times since 2020 Last updated: Oct 22, 2021 Started: Oct 19, 2017 Primary completion: Jan 31, 2023 Completion: Jan 31, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Multiple Myeloma and is currently ongoing. Affiliated Hospital of Jiangnan University leads this study, which shows 9 recorded versions since 2017 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

9 versions recorded

Jun 2025 — Present [monthly]

Unknown PHASE3
Mar 2025 — Jun 2025 [monthly]

Unknown PHASE3

Status: Recruiting → Unknown
Sep 2024 — Mar 2025 [monthly]

Recruiting PHASE3
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE3
Jun 2022 — Jul 2024 [monthly]

Recruiting PHASE3

▶ Show 4 earlier versions

Nov 2021 — Jun 2022 [monthly]

Recruiting PHASE3
Sep 2021 — Nov 2021 [monthly]

Recruiting PHASE3
Jan 2021 — Sep 2021 [monthly]

Recruiting PHASE3
Mar 2020 — Jan 2021 [monthly]

Recruiting PHASE3

First recorded

Oct 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Affiliated Hospital of Jiangnan University
Changshu Frist People's Hospital
Jiangsu Province Hospital of Traditional Chinese Medicine
Jiangyin People's Hospital
Jingjiang People's Hospital
Lianyungang Hospital Affiliated Bengbu Medical College
Nanjing Medical University
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd
Suzhou Municipal Hospital
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University
The Second People's Hospital of Huai'an
The Third People's Hospital of Kunshan
Zhangjiagang First People's Hospital

Data source: The First Affiliated Hospital of Soochow University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Suzhou, China