INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
A Phase I Study of the Adam-10 Inhibitor, INCB7839 in Children With Recurrent/Progressive High-Grade Gliomas to Target Microenvironmental Neuroligin-3
Sponsor: American Lebanese Syrian Associated Charities
Listed as NCT04295759, this PHASE1 trial focuses on Anaplastic Astrocytoma and Anaplastic Oligodendroglioma and remains completed. Sponsored by American Lebanese Syrian Associated Charities, it has been updated 23 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.
Status Flow
Change History
23 versions recorded-
Feb 2026 — Present [monthly]
Completed PHASE1
-
Sep 2025 — Feb 2026 [monthly]
Completed PHASE1
-
Aug 2025 — Sep 2025 [monthly]
Completed PHASE1
-
Mar 2025 — Aug 2025 [monthly]
Completed PHASE1
Status: Active Not Recruiting → Completed
-
Dec 2024 — Mar 2025 [monthly]
Active Not Recruiting PHASE1
▶ Show 18 earlier versions
-
Oct 2024 — Dec 2024 [monthly]
Active Not Recruiting PHASE1
-
Sep 2024 — Oct 2024 [monthly]
Active Not Recruiting PHASE1
-
Jul 2024 — Sep 2024 [monthly]
Active Not Recruiting PHASE1
-
May 2024 — Jul 2024 [monthly]
Active Not Recruiting PHASE1
-
Apr 2024 — May 2024 [monthly]
Active Not Recruiting PHASE1
-
Feb 2024 — Apr 2024 [monthly]
Active Not Recruiting PHASE1
-
Jun 2023 — Feb 2024 [monthly]
Active Not Recruiting PHASE1
Status: Recruiting → Active Not Recruiting
-
Apr 2023 — Jun 2023 [monthly]
Recruiting PHASE1
-
Feb 2023 — Apr 2023 [monthly]
Recruiting PHASE1
-
Dec 2022 — Feb 2023 [monthly]
Recruiting PHASE1
Status: Active Not Recruiting → Recruiting
-
Sep 2022 — Dec 2022 [monthly]
Active Not Recruiting PHASE1
-
May 2022 — Sep 2022 [monthly]
Active Not Recruiting PHASE1
Status: Recruiting → Active Not Recruiting
-
Feb 2022 — May 2022 [monthly]
Recruiting PHASE1
-
Oct 2021 — Feb 2022 [monthly]
Recruiting PHASE1
Status: Active Not Recruiting → Recruiting
-
Jan 2021 — Oct 2021 [monthly]
Active Not Recruiting PHASE1
-
Dec 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE1
Status: Recruiting → Active Not Recruiting
-
Jun 2020 — Dec 2020 [monthly]
Recruiting PHASE1
Status: Not Yet Recruiting → Recruiting
-
Apr 2020 — Jun 2020 [monthly]
Not Yet Recruiting PHASE1
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- American Lebanese Syrian Associated Charities
- National Cancer Institute (NCI)
- Pediatric Brain Tumor Consortium
For direct contact, visit the study record on ClinicalTrials.gov .