deltatrials
Terminated PHASE1 INTERVENTIONAL 8-arm NCT04301011

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors (RAPTOR)

A Phase 1/2a, Multicenter, Open-label Trial of TBio-6517, an Oncolytic Vaccinia Virus, Administered Alone and in Combination With Pembrolizumab, in Patients With Advanced Solid Tumors

Sponsor: Takeda

Updated 14 times since 2020 Last updated: Apr 17, 2025 Started: Jun 2, 2020 Primary completion: Jan 23, 2023 Completion: Jan 23, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision

A PHASE1 clinical study on Cervical Cancer and Cutaneous Squamous Cell Carcinoma, this trial is terminated or withdrawn. The trial is conducted by Takeda and has accumulated 14 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Mar 2022 · 9 months · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Mar 2023 · 11 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Dec 2023 · 8 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. May 2025 — Sep 2025 [monthly]

    Terminated PHASE1

    Phase: PHASE1/PHASE2PHASE1

  3. Sep 2024 — May 2025 [monthly]

    Terminated PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. Dec 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

    Status: Active Not RecruitingTerminated

Show 9 earlier versions
  1. Apr 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  3. Apr 2022 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  4. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jun 2021 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  9. Apr 2020 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Takeda
  • Turnstone Biologics, Corp.
Data source: Turnstone Biologics, Corp.

For direct contact, visit the study record on ClinicalTrials.gov .