deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04308785

A Study of Atezolizumab With or Without Tiragolumab Consolidation in Limited Stage Small Cell Lung Cancer

A Multicenter, Double-Blind, Placebo-Controlled, Randomized, Phase 2 Study to Investigate the Efficacy and Safety of Atezolizumab With or Without Tiragolumab as Consolidation Therapy in Patients With Limited Stage Small Cell Lung Cancer Who Have Not Progressed After Chemoradiotherapy

Sponsor: Hoffmann-La Roche

Conditions Carcinoma, Small Cell Lung
Interventions Atezolizumab Placebo Tiragolumab
Updated 35 times since 2020 Last updated: Oct 19, 2023 Started: Dec 1, 2021 Primary completion: Jul 25, 2023 Completion: Jul 25, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The sponsor's decision was based on the negative results of SKYSCRAPER-02.

Other terminated trials from Hoffmann-La Roche

See all terminations from Hoffmann-La Roche

Other Carcinoma, Small Cell Lung trials with similar outcome

Browse all Carcinoma, Small Cell Lung trials

Listed as NCT04308785, this PHASE2 trial focuses on Carcinoma, Small Cell Lung and remains terminated or withdrawn. Sponsored by Hoffmann-La Roche, it has been updated 35 times since 2021, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshot~Apr 2023 – ~Jul 2023 · 3 months · monthly snapshot~Jul 2023 – ~Oct 2023 · 3 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

35 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Nov 2023 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: Active Not Recruiting → Terminated

  5. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

▶ Show 30 earlier versions

  1. Jul 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Apr 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  5. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  6. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  7. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  8. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

  9. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  10. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

  11. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE2

  12. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  13. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  14. Oct 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE2

  15. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE2

  16. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE2

  17. May 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE2

  18. Apr 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE2

  19. Mar 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE2

  20. Feb 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  21. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE2

  22. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

  23. Nov 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE2

  24. Oct 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE2

  25. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE2

  26. Aug 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE2

  27. Jul 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE2

  28. Jun 2020 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE2

  29. May 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE2

  30. Apr 2020 — May 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Beijing, China , Changchun, China , Changsha, China , Chengdu, China , Chongqing, China , Fuzhou, China , Guangzhou, China , Harbin, China , Hefei, China , Jinan, China and 6 more locations