deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT04309474

A Safety and Efficacy Study of Intravenous (IV) Elezanumab Assessing Change in Neurologic Function in Adult Participants With Acute Ischemic Stroke (EAISE)

A Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Ischemic Stroke

Sponsor: AbbVie

Conditions Acute Ischemic Stroke
Interventions Elezanumab Placebo
Updated 28 times since 2020 Last updated: Dec 18, 2025 Started: Nov 9, 2020 Primary completion: Apr 18, 2024 Completion: Dec 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Acute Ischemic Stroke, this trial is completed. The trial is conducted by AbbVie and has accumulated 28 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 8 months · monthly snapshot

Change History

28 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Jan 2026 [monthly]

    Completed PHASE2

  3. Apr 2025 — Sep 2025 [monthly]

    Completed PHASE2

  4. Feb 2025 — Apr 2025 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

▶ Show 23 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Jul 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  4. Mar 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  5. Jan 2023 — Mar 2023 [monthly]

    Recruiting PHASE2

  6. Sep 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  7. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  8. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  9. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

  10. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  11. Nov 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  12. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  13. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  14. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  15. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

  16. Feb 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  17. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  18. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  19. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  20. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  21. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  22. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  23. Apr 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Albuquerque, United States , Allentown, United States , Barakaldo, Spain , Barcelona, Spain , Boston, United States , Busan, South Korea , Charlottesville, United States , Chicago, United States , Chikushino-shi, Japan and 29 more locations