deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT04311632

A Dose Escalation Study in de Novo Renal Transplantation

A 12-Month, Randomized, Controlled, Open-Label, Dose Escalation Study Evaluating Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of an Anti-CD2 Monoclonal Antibody, TCD601(Siplizumab) Compared to Anti-thymocyte Globulin (rATG), as Induction Therapy in de Novo Renal Transplant Recipients

Sponsor: ITB-Med LLC

Updated 14 times since 2020 Last updated: Feb 6, 2025 Started: May 26, 2021 Primary completion: Oct 3, 2023 Completion: Oct 3, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04311632, this PHASE2 trial focuses on Kidney Transplantation and remains completed. Sponsored by ITB-Med LLC, it has been updated 14 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Jul 2022 · 10 months · monthly snapshot~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Jun 2023 · 7 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshot~Mar 2024 – ~May 2024 · 2 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 14 months · monthly snapshot

Change History

14 versions recorded
  1. Mar 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. May 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

  5. Mar 2024 — May 2024 [monthly]

    Recruiting PHASE2

Show 9 earlier versions
  1. Nov 2023 — Mar 2024 [monthly]

    Recruiting PHASE2

  2. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

  3. Jun 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  4. Nov 2022 — Jun 2023 [monthly]

    Recruiting PHASE2

  5. Jul 2022 — Nov 2022 [monthly]

    Recruiting PHASE2

  6. Sep 2021 — Jul 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Mar 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE2

  8. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  9. Apr 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • ITB-Med LLC
Data source: ITB-Med LLC

For direct contact, visit the study record on ClinicalTrials.gov .