deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT04318327

BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma

Phase I, Open Label, Study of B-cell Maturation Antigen (BCMA)-Directed CAR-T Cells in Adult Patients With Multiple Myeloma

Sponsor: Novartis Pharmaceuticals

Conditions Multiple Myeloma
Interventions PHE885
Updated 27 times since 2020 Last updated: May 15, 2025 Started: Jul 23, 2020 Primary completion: Apr 29, 2025 Completion: Apr 29, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business decision

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Browse all Multiple Myeloma trials

A PHASE1 clinical study on Multiple Myeloma, this trial is terminated or withdrawn. The trial is conducted by Novartis Pharmaceuticals and has accumulated 27 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~May 2023 · 8 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Jun 2025 · 6 months · monthly snapshot~Jun 2025 – present · 13 months · monthly snapshot

Change History

27 versions recorded

  1. Jun 2025 — Present [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  2. Dec 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

▶ Show 22 earlier versions

  1. Dec 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

  2. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  3. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  4. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  5. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  6. May 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  7. Sep 2022 — May 2023 [monthly]

    Recruiting PHASE1

  8. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  9. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  10. Feb 2022 — May 2022 [monthly]

    Recruiting PHASE1

  11. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

  12. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE1

  13. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE1

  14. Feb 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  15. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  16. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  17. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

  18. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  19. Jul 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE1

  20. Jun 2020 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE1

  21. May 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE1

  22. Apr 2020 — May 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations