deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT04333914

Prospective Study in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 Infection (IMMUNONCOVID)

A Prospective, Controlled, Randomized, Multicenter Study of the Efficacy of an Autophagy Inhibitor (GNS561), an Anti-NKG2A (Monalizumab) and an Anti-C5aR (Avdoralimab) Compared to the Standard of Care in Patients With Advanced or Metastatic Cancer and SARS-CoV-2 (COVID-19) Infection.

Sponsor: Centre Leon Berard

Updated 9 times since 2020 Last updated: Sep 29, 2022 Started: Apr 15, 2020 Primary completion: Jul 6, 2021 Completion: Dec 31, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Advanced or Metastatic Hematological or Solid Tumor and SARS-CoV-2 (COVID-19) Infection and is currently completed. Centre Leon Berard leads this study, which shows 9 recorded versions since 2020 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2020 – ~Jun 2020 · 31 days · monthly snapshotRecruiting~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshotRecruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotSuspended~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Oct 2022 · 13 months · monthly snapshotActive Not Recruiting~Oct 2022 – ~Jul 2024 · 21 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Oct 2022 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Sep 2021 — Oct 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 4 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

    Status: SuspendedRecruiting

  2. Jul 2020 — Jan 2021 [monthly]

    Suspended PHASE2

    Status: RecruitingSuspended

  3. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  4. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

    First recorded

Apr 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Centre Leon Berard
Data source: Centre Leon Berard

For direct contact, visit the study record on ClinicalTrials.gov .