deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT04335084

A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection (HELPCOVID-19)

A Randomized, Double-Blind, Placebo-Controlled Phase IIa Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection

Sponsor: DSCS CRO

Updated 12 times since 2020 Last updated: Jun 4, 2025 Started: Jun 22, 2020 Primary completion: May 31, 2022 Completion: Apr 11, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates COVID and COVID-19 and is currently completed. DSCS CRO leads this study, which shows 12 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~May 2020 – ~Jun 2020 · 31 days · monthly snapshotNot Yet Recruiting~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshotNot Yet Recruiting~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshotRecruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotRecruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotRecruiting~Mar 2021 – ~Oct 2021 · 7 months · monthly snapshotRecruiting~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshotRecruiting~Nov 2021 – ~Jul 2024 · 32 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~Jul 2025 · 9 months · monthly snapshotActive Not Recruiting~Jul 2025 – present · 12 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Jul 2025 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Oct 2024 — Jul 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Nov 2021 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  2. Mar 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  4. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Jun 2020 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE2

  7. May 2020 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • DSCS CRO
  • ProgenaBiome
Data source: ProgenaBiome

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations