deltatrials
Completed PHASE1 INTERVENTIONAL 5-arm NCT04344795

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Phase 1a/1b Open Label Dose-escalation and Expansion Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Sponsor: Tempest Therapeutics

Updated 3 times since 2024 Last updated: Sep 5, 2025 Started: May 6, 2020 Primary completion: Sep 25, 2024 Completion: Sep 25, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Colorectal Cancer and Endometrial Cancer and is currently completed. Tempest Therapeutics leads this study, which shows 3 recorded versions since 2020 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotActive Not Recruiting~Nov 2024 – ~Oct 2025 · 11 months · monthly snapshotActive Not Recruiting~Oct 2025 – present · 7 months · monthly snapshotCompleted

Change History

3 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Nov 2024 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE1

    First recorded

May 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Tempest Therapeutics
Data source: Tempest Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .