deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT04349826

The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial) (ACT-South Asia)

Azithromycin and Cefixime Combination Versus Azithromycin Alone for the Out-patient Treatment of Clinically Suspected or Confirmed Uncomplicated Typhoid Fever in South Asia; a Randomised Controlled Trial

Sponsor: Department for International Development, United Kingdom

Conditions Typhoid Fever
Updated 8 times since 2020 Last updated: Jan 13, 2026 Started: May 23, 2021 Primary completion: Dec 31, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Typhoid Fever and is currently completed. Department for International Development, United Kingdom leads this study, which shows 8 recorded versions since 2021 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2020 – ~Jan 2021 · 8 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotNot Yet Recruiting~Nov 2022 – ~Jan 2024 · 14 months · monthly snapshotRecruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotRecruiting~Aug 2025 – ~Feb 2026 · 6 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshot

Change History

8 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE4

    Status: RecruitingCompleted

  2. Aug 2025 — Feb 2026 [monthly]

    Recruiting PHASE4

  3. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  5. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE4

Show 3 earlier versions
  1. Nov 2022 — Jan 2024 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  2. Jan 2021 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE4

  3. May 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Department for International Development, United Kingdom
  • Medical Research Council
  • Oxford University Clinical Research Unit, Vietnam
  • University of Oxford
  • Wellcome Trust
Data source: Oxford University Clinical Research Unit, Vietnam

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations