deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT04365933

A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir

A Phase 2a Open-label Study of the Oral Farnesoid X Receptor (FXR) Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B (CHB) Patients in Combination With Pegylated Interferon alpha2a (Peg-IFN) Alone and With Entecavir (ETV)

Sponsor: Enyo Pharma

Updated 11 times since 2020 Last updated: Aug 22, 2022 Started: May 25, 2020 Primary completion: Jun 16, 2021 Completion: Nov 29, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Hepatitis B, Chronic and is currently completed. Enyo Pharma leads this study, which shows 11 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~May 2020 – ~Jul 2020 · 2 months · monthly snapshotNot Yet Recruiting~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshotRecruiting~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshotRecruiting~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotRecruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotRecruiting~May 2021 – ~Oct 2021 · 5 months · monthly snapshotActive Not Recruiting~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Oct 2021 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

Show 6 earlier versions
  1. May 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  3. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  4. Aug 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  5. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. May 2020 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Enyo Pharma
Data source: Enyo Pharma

For direct contact, visit the study record on ClinicalTrials.gov .