deltatrials
Unknown PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT04368819

Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms (ARAMIS)

A Single-center, Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Allopurinol in Improving Ischemic Symptoms in Patients With Refractory Angina.

Sponsor: Fundação de Amparo à Pesquisa do Estado de São Paulo

Conditions Refractory Angina
Interventions Allopurinol 300 MG Placebo oral tablet
Updated 8 times since 2020 Last updated: Feb 23, 2021 Started: Mar 3, 2021 Primary completion: Sep 30, 2021 Completion: Dec 31, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Refractory Angina and is currently ongoing. Fundação de Amparo à Pesquisa do Estado de São Paulo leads this study, which shows 8 recorded versions since 2021 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2020 – ~Jun 2020 · 31 days · monthly snapshotEnrolling By Invitation~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotEnrolling By Invitation~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotEnrolling By Invitation~Mar 2021 – ~Mar 2023 · 24 months · monthly snapshotRecruiting~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown PHASE2/PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE2/PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2/PHASE3

    Status: Unknown Status → Unknown · Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  4. Mar 2023 — Jul 2024 [monthly]

    Unknown Status PHASE2_PHASE3

    Status: Recruiting → Unknown Status

  5. Mar 2021 — Mar 2023 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Enrolling By Invitation → Recruiting

▶ Show 3 earlier versions

  1. Jan 2021 — Mar 2021 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

  2. Jun 2020 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

  3. May 2020 — Jun 2020 [monthly]

    Enrolling By Invitation PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Fundação de Amparo à Pesquisa do Estado de São Paulo
  • InCor Heart Institute
  • Ministry of Health, Brazil
Data source: Ministry of Health, Brazil

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations