deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT04377932

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Interleukin-15 Armored Glypican-3-specific Chimeric Antigen Receptor Expressing Autologous T Cells as Immunotherapy for Children With Solid Tumors

Sponsor: Baylor College of Medicine

Interventions AGAR T cells
Updated 17 times since 2020 Last updated: Jan 20, 2026 Started: Aug 8, 2021 Primary completion: Aug 17, 2024 Completion: Aug 26, 2040
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04377932, this PHASE1 trial focuses on Liposarcoma and Liver Cancer and remains ongoing. Sponsored by Baylor College of Medicine, it has been updated 17 times since 2021, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2020 – ~Dec 2020 · 6 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Mar 2023 · 10 months · monthly snapshot~Mar 2023 – ~Aug 2023 · 5 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Nov 2025 · 6 months · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

17 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Dec 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. May 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  5. Sep 2024 — May 2025 [monthly]

    Recruiting PHASE1

Show 12 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  2. Aug 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

  3. Mar 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  4. May 2022 — Mar 2023 [monthly]

    Recruiting PHASE1

  5. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1

  6. Jan 2022 — Apr 2022 [monthly]

    Recruiting PHASE1

  7. Nov 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  8. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  9. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1

  10. Jan 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1

  11. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

  12. Jun 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor College of Medicine
  • Center for Cell and Gene Therapy, Baylor College of Medicine
  • National Institutes of Health (NIH)
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations