Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer
A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients With Metastatic Castrate Resistant Prostate Cancer
Sponsor: Arcus Biosciences, Inc.
Listed as NCT04381832, this PHASE1/PHASE2 trial focuses on Androgen-Resistant Prostatic Neoplasms and Castration Resistant Prostatic Neoplasms and remains completed. Sponsored by Arcus Biosciences, Inc., it has been updated 28 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.
Status Flow
Change History
28 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE1/PHASE2
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Aug 2025 — Sep 2025 [monthly]
Completed PHASE1/PHASE2
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Oct 2024 — Aug 2025 [monthly]
Completed PHASE1/PHASE2
Status: Active Not Recruiting → Completed
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Sep 2024 — Oct 2024 [monthly]
Active Not Recruiting PHASE1/PHASE2
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Jul 2024 — Sep 2024 [monthly]
Active Not Recruiting PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
▶ Show 23 earlier versions
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Jun 2024 — Jul 2024 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Mar 2024 — Jun 2024 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Oct 2023 — Mar 2024 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Sep 2023 — Oct 2023 [monthly]
Active Not Recruiting PHASE1_PHASE2
Status: Recruiting → Active Not Recruiting
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May 2023 — Sep 2023 [monthly]
Recruiting PHASE1_PHASE2
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Feb 2023 — May 2023 [monthly]
Recruiting PHASE1_PHASE2
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Dec 2022 — Feb 2023 [monthly]
Recruiting PHASE1_PHASE2
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Sep 2022 — Dec 2022 [monthly]
Recruiting PHASE1_PHASE2
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Jun 2022 — Sep 2022 [monthly]
Recruiting PHASE1_PHASE2
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Mar 2022 — Jun 2022 [monthly]
Recruiting PHASE1_PHASE2
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Jan 2022 — Mar 2022 [monthly]
Recruiting PHASE1_PHASE2
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Dec 2021 — Jan 2022 [monthly]
Recruiting PHASE1_PHASE2
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Nov 2021 — Dec 2021 [monthly]
Recruiting PHASE1_PHASE2
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Oct 2021 — Nov 2021 [monthly]
Recruiting PHASE1_PHASE2
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Sep 2021 — Oct 2021 [monthly]
Recruiting PHASE1_PHASE2
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Jun 2021 — Sep 2021 [monthly]
Recruiting PHASE1_PHASE2
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Mar 2021 — Jun 2021 [monthly]
Recruiting PHASE1_PHASE2
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Jan 2021 — Mar 2021 [monthly]
Recruiting PHASE1_PHASE2
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Nov 2020 — Jan 2021 [monthly]
Recruiting PHASE1_PHASE2
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Oct 2020 — Nov 2020 [monthly]
Recruiting PHASE1_PHASE2
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Aug 2020 — Oct 2020 [monthly]
Recruiting PHASE1_PHASE2
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Jul 2020 — Aug 2020 [monthly]
Recruiting PHASE1_PHASE2
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Jun 2020 — Jul 2020 [monthly]
Recruiting PHASE1_PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Arcus Biosciences, Inc.
- Gilead Sciences
For direct contact, visit the study record on ClinicalTrials.gov .