deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT04396340

First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2b

A Phase 1b, First-in-Human, Dose Escalation and Expansion Study of XMT-1592 In Patients With Solid Tumors Likely to Express NaPi2b

Sponsor: IQVIA Biotech

Interventions XMT-1592
Updated 13 times since 2020 Last updated: Mar 14, 2024 Started: May 11, 2020 Primary completion: Sep 30, 2022 Completion: Sep 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

discontinued development program

Listed as NCT04396340, this PHASE1 trial focuses on Nonsmall Cell Lung Cancer and Ovarian Cancer and remains terminated or withdrawn. Sponsored by IQVIA Biotech, it has been updated 13 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~May 2022 · 11 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Nov 2023 · 9 months · monthly snapshot~Nov 2023 – ~Apr 2024 · 5 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Apr 2024 — Jul 2024 [monthly]

    Terminated PHASE1

    Phase: PHASE1_PHASE2PHASE1

  4. Nov 2023 — Apr 2024 [monthly]

    Terminated PHASE1_PHASE2

    Status: Active Not RecruitingTerminated

  5. Feb 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

Show 8 earlier versions
  1. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Jun 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  3. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jun 2021 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Feb 2021 — Jun 2021 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jun 2020 — Nov 2020 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

May 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • IQVIA Biotech
  • Mersana Therapeutics
Data source: Mersana Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations