deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04396366

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

A Randomized, Subject- and Investigator-blinded, Placebo-controlled, Parallel Group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Patients With Bronchiectasis

Sponsor: Innovative Medicines Initiative

Conditions Bronchiectasis
Interventions Placebo QBW251
Updated 27 times since 2020 Last updated: Sep 24, 2025 Started: Feb 2, 2021 Primary completion: Jun 15, 2023 Completion: Jun 21, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Strategic business decision

A PHASE2 clinical study on Bronchiectasis, this trial is terminated or withdrawn. The trial is conducted by Innovative Medicines Initiative and has accumulated 27 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~May 2022 · 4 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~May 2023 · 6 months · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

27 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Terminated PHASE2

  3. Apr 2025 — Sep 2025 [monthly]

    Terminated PHASE2

  4. Sep 2024 — Apr 2025 [monthly]

    Terminated PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

Show 22 earlier versions
  1. Sep 2023 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  2. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  4. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  5. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  6. Nov 2022 — May 2023 [monthly]

    Recruiting PHASE2

  7. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE2

  8. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  9. Jan 2022 — May 2022 [monthly]

    Recruiting PHASE2

  10. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  11. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  12. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  13. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  14. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  15. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

  16. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  17. Feb 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  18. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE2

  19. Nov 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

  20. Oct 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE2

  21. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE2

  22. Jun 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Innovative Medicines Initiative
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .