deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT04396899

Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Failure (BioVAT-HF)

Sponsor: Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Conditions Heart Failure
Interventions EHM implantation
Updated 10 times since 2020 Last updated: Feb 19, 2026 Started: Feb 3, 2020 Primary completion: Dec 31, 2027 Completion: Dec 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Heart Failure and is currently actively recruiting participants. Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) leads this study, which shows 10 recorded versions since 2020 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2022 · 15 months · monthly snapshotRecruiting~Jun 2022 – ~Apr 2023 · 10 months · monthly snapshotRecruiting~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotRecruiting~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshot

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. Jun 2025 — Feb 2026 [monthly]

    Recruiting PHASE1/PHASE2

    Status: UnknownRecruiting

  3. Apr 2025 — Jun 2025 [monthly]

    Unknown PHASE1/PHASE2

    Status: RecruitingUnknown

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

Show 5 earlier versions
  1. Apr 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  2. Jun 2022 — Apr 2023 [monthly]

    Recruiting PHASE1_PHASE2

  3. Mar 2021 — Jun 2022 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  4. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  5. Jun 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Feb 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
  • Repairon GmbH
  • University Medical Center Freiburg
  • University Medical Center Goettingen
Data source: University Medical Center Goettingen

For direct contact, visit the study record on ClinicalTrials.gov .