deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT04397679

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

Treatment of Adults with Newly Diagnosed Glioblastoma with Partial Brain Radiation Therapy Plus Temozolomide and Chloroquine Followed by Tumor Treating Fields Plus Temozolomide and Chloroquine -- a Pilot Study

Sponsor: Barbara Ann Karmanos Cancer Institute

Updated 11 times since 2020 Last updated: Jan 13, 2025 Started: Aug 12, 2021 Primary completion: May 14, 2024 Completion: May 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

slow accrual

This PHASE1 trial investigates Glioblastoma and Gliosarcoma and is currently terminated or withdrawn. Barbara Ann Karmanos Cancer Institute leads this study, which shows 11 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jun 2023 · 9 months · monthly snapshotRecruiting~Jun 2023 – ~Apr 2024 · 10 months · monthly snapshotRecruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – present · 17 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Feb 2025 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  2. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Jun 2023 — Apr 2024 [monthly]

    Recruiting PHASE1

Show 6 earlier versions
  1. Sep 2022 — Jun 2023 [monthly]

    Recruiting PHASE1

  2. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Sep 2021 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE1

  4. Mar 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1

  5. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE1

  6. Jun 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Barbara Ann Karmanos Cancer Institute
Data source: Barbara Ann Karmanos Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations