deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT04398108

A Study to Evaluate the Pharmacokinetics of Margetuximab in Chinese Patients With HER2+ MBC

An Open-Label, Single-arm, Phase I Study to Evaluate the Pharmacokinetics, Tolerability and Safety of Margetuximab Plus Chemotherapy in the Treatment of Chinese Patients With HER2+ Metastatic Breast Cancer Who Have Received Prior Anti-HER2 Therapies

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Updated 8 times since 2020 Last updated: Jun 11, 2021 Started: Aug 25, 2020 Primary completion: Apr 27, 2021 Completion: Apr 27, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates HER2 Positive Metastatic Breast Cancer and is currently completed. Zai Lab (Shanghai) Co., Ltd. leads this study, which shows 8 recorded versions since 2020 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2020 – ~Dec 2020 · 6 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotRecruiting~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotCompleted~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Sep 2021 — Oct 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Mar 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

Show 3 earlier versions
  1. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Jun 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Zai Lab (Shanghai) Co., Ltd.
Data source: Zai Lab (Hong Kong), Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .