Completed PHASE2 INTERVENTIONAL 6-arm NCT04417530

Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

A Phase 2 Open-label, Ascending Single and Repeat Dose Escalation Trial of Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

Sponsor: Aura Biosciences

Conditions Choroidal Melanoma Ocular Melanoma Uveal Melanoma

Interventions AU-011 PDT Laser Suprachoroidal Microinjector

Updated 20 times since 2020 Last updated: Feb 27, 2025 Started: Aug 5, 2020 Primary completion: Apr 22, 2024 Completion: Apr 22, 2024

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Choroidal Melanoma and Ocular Melanoma and is currently completed. Aura Biosciences leads this study, which shows 20 recorded versions since 2020 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

20 versions recorded

Apr 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Apr 2025 [monthly]

Completed PHASE2

Status: Active Not Recruiting → Completed
Jul 2024 — Sep 2024 [monthly]

Active Not Recruiting PHASE2
Jan 2024 — Jul 2024 [monthly]

Active Not Recruiting PHASE2
Jul 2023 — Jan 2024 [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting

▶ Show 15 earlier versions

Jan 2023 — Jul 2023 [monthly]

Recruiting PHASE2
May 2022 — Jan 2023 [monthly]

Recruiting PHASE2
Mar 2022 — May 2022 [monthly]

Recruiting PHASE2
Jan 2022 — Mar 2022 [monthly]

Recruiting PHASE2
Dec 2021 — Jan 2022 [monthly]

Recruiting PHASE2
Nov 2021 — Dec 2021 [monthly]

Recruiting PHASE2
Oct 2021 — Nov 2021 [monthly]

Recruiting PHASE2
Apr 2021 — Oct 2021 [monthly]

Recruiting PHASE2
Feb 2021 — Apr 2021 [monthly]

Recruiting PHASE2
Jan 2021 — Feb 2021 [monthly]

Recruiting PHASE2
Dec 2020 — Jan 2021 [monthly]

Recruiting PHASE2
Nov 2020 — Dec 2020 [monthly]

Recruiting PHASE2
Oct 2020 — Nov 2020 [monthly]

Recruiting PHASE2
Sep 2020 — Oct 2020 [monthly]

Recruiting PHASE2

Status: Not Yet Recruiting → Recruiting
Jul 2020 — Sep 2020 [monthly]

Not Yet Recruiting PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Aura Biosciences

Data source: Aura Biosciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Atlanta, United States , Aurora, United States , Boston, United States , Carmel, United States , Chicago, United States , Dallas, United States , Greenville, United States , Houston, United States , Iowa City, United States and 12 more locations