deltatrials
Completed PHASE1 INTERVENTIONAL 5-arm NCT04441905

Phase 1 Study of SAR440894 vs Placebo

A Phase 1, Randomized, Double-Blind, Multi-Site, Single Dose Escalation Study to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of SAR440894 vs Placebo in Healthy Adults

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions Chikungunya Virus Infection
Interventions Placebo SAR440894
Updated 47 times since 2020 Last updated: Dec 18, 2025 Started: Oct 14, 2020 Primary completion: Aug 22, 2024 Completion: Aug 22, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Chikungunya Virus Infection and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 47 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Oct 2022 · 30 days · monthly snapshot~Oct 2022 – ~Nov 2022 · 31 days · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Dec 2023 · 4 months · monthly snapshot~Dec 2023 – ~Mar 2024 · 3 months · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jun 2025 · 8 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Jan 2026 · 3 months · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

47 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed PHASE1

  2. Jan 2026 — Feb 2026 [monthly]

    Completed PHASE1

  3. Oct 2025 — Jan 2026 [monthly]

    Completed PHASE1

  4. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE1

  5. Jun 2025 — Sep 2025 [monthly]

    Completed PHASE1

▶ Show 42 earlier versions

  1. Oct 2024 — Jun 2025 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  2. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  6. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  7. Dec 2023 — Mar 2024 [monthly]

    Recruiting PHASE1

  8. Aug 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  9. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  10. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

  11. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  12. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE1

  13. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE1

  14. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1

  15. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE1

  16. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  17. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  18. Oct 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  19. Sep 2022 — Oct 2022 [monthly]

    Recruiting PHASE1

  20. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  21. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  22. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  23. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1

  24. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE1

  25. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE1

  26. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE1

  27. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  28. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE1

  29. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE1

  30. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  31. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  32. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  33. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE1

  34. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1

  35. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  36. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1

  37. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  38. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  39. Oct 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE1

  40. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE1

  41. Aug 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE1

  42. Jul 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations